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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8bd59428b038ea5ce681351e017e1bbef52d760d1449f20c83adefb611efbea' 
  AND token = 'l+bzHR4m+lRHP/4bRGxG3GvzBsvNLutbT3Gc755kAAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}