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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e61a4221a4ad40c432aa9661a1b06f5f78483e41522d6f27fd76e4d5aff88106' 
  AND token = 'M2Je3lP+wtHL9WsnZ4/sK0WPJgaTEPONGf1A7eezYPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}