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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5efe944bdd300f54b57d81e2ccd5aaf64ff5487dd9ca24e2cd957b909bd18d' 
  AND token = 'qWJeeBfKOAS3o9ZaH5rDPRLKSY1MO29phj6tdG1nPPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}