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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbbd5e36091e877d2abc0529de5cb8b4d61f2e6f576a82ff0febf59240778e75' 
  AND token = 'cARShhf8rKDxT40OfFy1b5+3hleED27+GW1poFMcPFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}