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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4a02ee621c0c69fa2b5d1ee95545c0318fc529d999f31b5213d0fcaba5ceb2' 
  AND token = 'OEaJNHwP2r3+jSHtnYup0uWUKZcjGbXM9LMoPVfWCk8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}