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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '379eb98cb25e2f98c3617897ece0ce78b45551af0ceeaceeabe3d24941815f98' 
  AND token = 'MkMWQK5F/olJoEbbpGRFA9GallJFK1GC3an7ZqgsKuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}