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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7567ddbeb5eb48f4a3663e6fa9735ab00bf38d226347e107c5346302e2e7207e' 
  AND token = 'sdn0DOwh6Oi+ufRJPJOEitNMSpTmbR51CfSKLNs0f+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}