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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f4decc1caa4dc057fd73eb5983c022c88876fc72caa0f3e22c36253395e080' 
  AND token = 'FHexdFDdW2HvyItmkEE7IHAukcpqTTE5femlnRCN1mQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}