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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8ad0a0998e11358b97e086b20af2d49bf08c3f0b7e701e51fe976ad37f96cb9' 
  AND token = 'iqm7HT0USJUvqo+rRkpzj7lRJz8HGUfXITk/YHlKHTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}