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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee7ae6018d8470cf7041835f526b62e97645f8604e1c05e22155c080fa4e3322' 
  AND token = '7zGfDtKYy+DCuhFK1Sfm2UD/K/XeeKgVrY6x+f8m078=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}