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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f7788df4b5725d119b27f0667fd7231bfb48c52b2d1123ca2cca3657240c1be' 
  AND token = 'DZD0wY1mylVssPfJYm5xY6hrQyF7bjfNzObUFW/ws74=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}