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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e5f67e37e02d66c8d7e6531e215eb9b53ca3269b81ec3ed24583f7111c6690c' 
  AND token = 'oZheYv2Bn1hFfI9EVtrDjvSljUVX3c4pB+RCoc1dc+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}