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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7664a6f9962230693f9646f71c07973fce61f87a62bca67586cc3f26b66ff801' 
  AND token = 'MS3BMPB5I20/9LFbC2j86ZTEGBOl0PbdBCZkEygCd20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}