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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '30f127c78095ee1fb21c509bdaa25e0dc242b46903210dae8d3a9036721c194f' 
  AND token = 'O0zIQvxBV2oOOkwdTdS+pT8CPQNjUU31RAQ/UFn0+vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}