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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec2a1b36a7ce62ec7e45a800014de389d2944d6a3501d69508cb3aaed90ef02' 
  AND token = 'Jl0Wzg6WOufsEWepj+GhO4zFYG6H0I86/93wGxKMXBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}