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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '647022b420d9cc5d5f2f9ee4a74c8478691804ead83f57ae24290538e71fcdac' 
  AND token = 'pNJP6PuG0WyP8s2b2GioH9KLHzkxxaSGfSOmt3D/51k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}