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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17c2566cb3a903f64c23148228aebc7a8cddde3041f716a885f65c007b607ac6' 
  AND token = '7xBwUIIoiJbVYtCpb2//IGETsxboj3rf+dyYNbgPlpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}