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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046219a1ada7e07b9bf0af9070197d32fa9dae803b003aefb17be8ce43b1c652' 
  AND token = 'Z5YIZsCS20+8dFsWOgDB7MXr1kNAar1hfY0Kf5P61lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}