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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dcfd0e728416a004ec30cda121b65968b90112c168df10e1069817af9f0f9cd5' 
  AND token = 'iV0rsjmWqxxZ9MGg2ESeV9fAxO11/CeenVGq3a0g2Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}