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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57143c1077ef912eb3195d6614525c80a3301c8dc728f411c11377a1c6e5eeca' 
  AND token = '5MMSNVeoTmAY6R2Mi6w4PDna4WTCXlhHwUeF6yKw2g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}