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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a27beab850eb53956a1503c55f1039ead2f7f0f5d63c20a50aaf85f7c1997d2' 
  AND token = 'WZM9txPVNg6+xE/kNWz8Kt2iUnHitwMin79rRRyeM4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}