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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be3f73a2984d3cb893b77cc06741bc53dabd562d029e74b1577ac01b1c96a695' 
  AND token = '8epkelX76NfN21iGpowPg/8p8RcryvrgnyVlht2oLCM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}