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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fad7bc2e1986cf3e8d27bfbfe1a152f4642e76cb2e446042551cdd3f5b6b190' 
  AND token = '5hOfuGTtLos18aass+drzZv4h2KcMOH23IzCKcTwET0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}