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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46bea2cd96e538b665c8857af8b7d1eefe26af3971e243ac25ce73c9523b2811' 
  AND token = 'Nua2s1pBK7BgUsg5X0EazSDcAeExhG7kN8YLWgc3/Cc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}