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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a7a58ebba72661dfbe94765f38ec1991ee5c376726fba1f8c4e1ca0f141518a' 
  AND token = 'hHvxeQhi5Ai1fEH+Cy3I1uQ9Hc+kSPvuJ3hhXNTwtLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}