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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8fb42d9ecf16c33b51732863ea97ad3d5e0b553a7ed78871c144741fc7f4a2' 
  AND token = 'OHcmq4zlpEFHwLQd29mb0DApGjtsdYIWyiAvOeFby8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}