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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cad41a11362fe797b50c168deecae9321ca15aef4f00d2f8d578d6fc1eed7c80' 
  AND token = 'bxfgHQXYXJaPeWz/bR9mvztyLMK6uQB2OIqhxIbOeO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}