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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe1ed11f1d3c5715b607963809dc90814a27b962aa73eb02e34fdd9774a14f6' 
  AND token = 'JESRJc8XD5F47Gd/F5XkoUKtLmJRM6H/PRPuywwEM0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}