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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b77144f67762fa49573715d6bc47e4b5a9f6e19cbf52b5de7af82c53086e6d1f' 
  AND token = 'Ub7KICj3Z06oCdkE30zhlOV5xoPWgltMlPrXrcbmadg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}