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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6ae42157b8cfcb1561caafe9d9744379d7cf292d47e95a053e45e4216e04d09' 
  AND token = '7noXvmQa3tHCFCxH9ICuoorhXLy/eesAHNiArg6ZROg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}