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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21409e8cede52d570a90bbba5df0084b458e23582c53c09dd431a95bb7aad56a' 
  AND token = 'UqOIwQG2iQvBS2RsRxqGlbOuxHUPIMzGFG7Zh8ul8pE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}