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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e6a0bd1d0bb87065cbef16296b2e238e733ea770f20350cb9c6152b39c2c09' 
  AND token = 'E0MAPCqdJ0BaN3nxuoAuYEkF0WkJjB8mMFU2EacRhvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}