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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74989c716a101cc3b57ad6dc27bdb18a22f6a6188a475db9704a43b05eb22fd8' 
  AND token = 'W2NQav3M2/2MOVu3v/7DUu5FLZ2i6V3rb6XL4uD77WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}