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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2907104ba297a93f4e82fd685f97ab79e4a20261f94882efc518dbc3b31fa4f' 
  AND token = 'La1FHhS+ZIUHIQhH0v7f5oKa1N8exeoaEcSQGvSGBFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}