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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9bc3b637021c889ca605fbced887eec6fc063ec44288cdcbc052a81535577cf' 
  AND token = 'qWO0gew9HGVlu3kr0tAk6Kma1vWJR8x7LQq5Q9ZxEQg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}