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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e4a2a00a9cc58defe1fc4ce685d54495c92d3b51f2fd0984c9838b15f09b01f' 
  AND token = 'NzZWb8Cm8kyNvZZyk8tj3V9Oyb+i4tM4mSKGHnf1R8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}