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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ea8efd620707d0ebd7a628d593017e80d592bb1eed4ff6b75e1515dfef8e6f6' 
  AND token = '+co22QmqrxlUIG0BnRobodhocqz/sF0gmFuw9FILa+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}