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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2795508f2ea43e244ed95c62843f48a8694b1779735b65f18e9d2b51277a242b' 
  AND token = 'eQrUDR5EX0KtKob0x5/PXReBbJvVIQ2umo5At5DWHSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}