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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5c8949f9f6014882d7459a8fbf4a44a0a512cf66af1939a46f919b431adad1c' 
  AND token = 'ZDcwQtSAJtKUbfTp6mFtyHmepk1e9qeDUzbKodbJh6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}