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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '376f94cdff55cc1546b297995dad49a66c105b6089ba7aab5c382a19a08f59b2' 
  AND token = '3VOvsZ0a0NJpeGL9VDw5OS2Urlo/ZBnVO2Fw+cAzWr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}