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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65dfa75998448458a1adc44eff176b7e9c0a87122fa79e88da1cddc0402f30e6' 
  AND token = '8eES/mEaG2S9//bjXbr9LiFzEXL7JIEwS0biwiqx+BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}