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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14870a34756e9731e187733e3be3de9ae3dd325dd1fc06826df2b3e4963bfef3' 
  AND token = 'eNPD9fxA7dzb4RycFKODAKiHcP/RjJVBKNfUGDz5404=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}