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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251ed241dd64b70d3fe18806e99e76449446a396570cee6e6ff16d015d91f5c2' 
  AND token = 'M/ndtsJOCKsPw2VGCq+eBQARII2FR9dOFM2tO0UL9jA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}