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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '104ef23f583247994dff40263bacf109fa9ef677346583af51bf70a49c048647' 
  AND token = 'jLCsm4U9wRBPkEcyMkf1tejirF/Ss14tQCFmWzt9g+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}