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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34de4814fa336809802b56fdd50726f191fe05eb2c58f27c4e7d60cc334831f5' 
  AND token = 'kGty3P26IDIv07F1gNcIfxuChN6YLgtAsWCiTAm/9lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}