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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90d8fd1d509fe9a54d26a57895795ca225eee30bd30ecaa19db556b1a5d8c850' 
  AND token = 'Jx4s/qTm5l/TwW+DKPPmQzt0vzGRHta3MP/M9roIFEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}