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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b7afce0e70c78b35a802574710664cc63b9f16e46c7ef305ffd44ab83dc01d9' 
  AND token = 'CTpsT+B3RsIVcsaPO1/FIDPADGg/O3HBh8ybkWdpDvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}