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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1507726d93e6dac71a5d364f4afdd14c633a99dbfbe133aafac8e2dcc798db2' 
  AND token = '7Jb28VIUXCt2u8cvpZ9DUdpjRBnYwilxpErbp19e1SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}