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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fe191ca631c53e98fedab32da10776581852227a490f0ebd9f47f39af93ce1d' 
  AND token = '7hGqlf3qEIUJON7r4H8o1UeAHrBpNdVjxxG0R9Q3CVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}