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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bb755b1b1ac80007aeb0b97600ee8f30662e047ed2165d9f854877d3ff3fa548' 
  AND token = '0AvhNQ+Xf/H3YaHpB/iR9AIWRIs/RaGE1DlIxL69fA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}